Additional file 7 of Calcineurin depletion coincides with phosphorylated TDP-43 deposition in a mouse model of ALS/FTLD-TDP
Abstract
Supplementary Material 7. Figure S7: Activation of calcineurin using an independent transgene protects against TDP-43 neurotoxicity in C. elegans. a A second transgene overexpressing wildtype TAX-6 in C. elegans (tax-6 o/ex 2) improves TDP-43 Tg motor dysfunction. Statistical analysis is by unpaired t-test, two-tailed (n ≥ 150; N = 3 independent experiments; *: p < 0.05).
Fields of Study & Subjects
Amyotrophic Lateral Sclerosis Research
Alzheimer's disease research and treatments
Muscle Physiology and Disorders
Publication details
- Journal / source
- Figshare
- Publication date
- 1 January 2026