Atlas of Lymph Node Cytopathology : Methodological Principles and Diagnostic Applications in Hematopathology

Abstract / SummaryThis publication presents the foundational sections of the "Atlas de cytopathologie ganglionnaire" (Atlas of Lymph Node Cytopathology), a comprehensive clinical manual dedicated to the study of inflammatory and tumorous lymph node pathologies, specifically Hodgkin and non-Hodgkin malignant lymphomas.The work emphasizes the critical role of fine-needle aspiration (FNA) and lymph node imprinting as rapid, high-precision diagnostic tools that complement traditional histopathology. By leveraging May-Grünwald Giemsa (MGG) staining and immunocytochemical markers, the atlas provides a detailed framework for identifying cellular structures and guiding clinical orientation.Key Contents Included:Methodological Principles: Technical guidelines for material collection and preparation.Normal and Reactional Tissue: Analysis of functional lymph node tissue and immune responses.Malignant Non-Hodgkin Lymphomas: Histological classifications, cytological diagnostic criteria, and clinical-therapeutic aspects for B-cell, T-cell, and NK-cell lineages.Hodgkin’s Disease: Detailed diagnostic criteria and the specific contribution of cytological analysis.Special Cases: Lymphomas associated with immunodeficiency (including HIV and transplantation) and non-lymphoid lesions such as metastatic tumors.Core Medical KeywordsHematopathologyLymph Node CytopathologyMalignant LymphomaHodgkin's DiseaseNon-Hodgkin Lymphoma (NHL)Fine-Needle Aspiration (FNA)Technical & Diagnostic KeywordsCytological DiagnosisLymph Node ImprintMay-Grünwald Giemsa (MGG) StainingImmunocytochemistryHistological ClassificationMetastatic TumorsFunctional & Clinical KeywordsLymphoid ReactionImmune ResponseImmunodeficiency-Associated LymphomasDiagnostic MethodologyClinical Hematology