Additional file 1 of IbinA and IbinB regulate the Toll pathway-mediated immune response in Drosophila melanogaster

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Authors: Matthew K. Maasdorp, Susanna Valanne, Laura Vesala, Petra Vornanen, Elina Haukkavaara, Tea Tuomela, Aino Malin, Tiina Susanna Salminen, Dan Hultmark, Mika Rämet
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Abstract

Additional file 1. Figures S1-S7. FigS1. Ibin open reading frames. FigS2. Chromosomal location of Ibin and Mibin genes in different species. FigS3. Mibin open reading frames. FigS4. IbinB expression is dependent on functional Imd pathway. IbinA shows varied expression upon exposure to various stressors. FigS5. Example images of Ibin mutant phenotypes. Flow cytometric analysis of larval hemocytes in Ibin mutants and controls. FigS6. Additional heatmaps of immune-relevant genes at 36hpi with L. monocytogenes infection in Ibin mutants and controls. FigS7. qPCR verification of eater and Drs expression at 36hpi with L. monocytogenes infection. Survival of eater and Diedel mutant flies from L. monocytogenes infection.

Fields of Study & Subjects

Invertebrate Immune Response Mechanisms Immune Response and Inflammation Neurobiology and Insect Physiology Research

Publication details

Journal / source
Figshare
Publication date
1 January 2026