Additional file 3 of Risk stratification for endometrial cancer: independent and joint effects of polygenic risk score and body mass index in 129,829 UK Biobank participants
Abstract
Additional file 3: Supplementary Note. Sensitivity analyses using reported age of menopause and measured SHBG and testosterone levels instead of polygenic scores for these variables. Includes Table 1 comparing discriminative performance of prediction models and Figs. 1–2 demonstrating that BMI and PRS independently associate with endometrial cancer risk without evidence of interaction.
Fields of Study & Subjects
Cancer Risks and Factors
Genetic Associations and Epidemiology
Endometrial and Cervical Cancer Treatments
Publication details
- Journal / source
- Figshare
- Publication date
- 10 February 2026
- Language
- EN