Additional file 3 of Chitinase-3-like protein 1 depletion in glioma cells alters tumor microenvironment and normalizes neovasculature in human glioma xenografts

Supplementary Material 3: Figure 3. a. Correlation analysis for VEGFA and CHI3L1 expression in Ivy GAP RNAseq database. b. Correlation analysis for mVEGF and mCHI3L1 in the sera of tumor-bearing mice. c. Immunofluorescent staining for Ki67, a mitosis/proliferation marker, in green. Scale bar represents 150 μm. Enlarged regions of interest depicting nuclear staining are presented below. d. Linear regression analysis of CHI3L1 and SPP1 mRNA expression in 14 human primary cell lines described elsewhere [27].