Additional file 6 of Spatiotemporal transcriptomic mapping reveals region-specific glial activation and astrocyte shifts in epileptogenesis beyond the hippocampus

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Authors: Adrien Dufour, Christophe Le Priol, Baptiste Porte, Ronan Jouanard, Julien Maurizio, Anne-Elodie Receveur, Stéphane Auvin, Juliette Van Steenwinckel, Pierre Gressèns, Andrée Delahaye-Duriez
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Abstract

Supplementary Material 6: Supplementary Fig. 6. Heatmap of SE dysregulated genes grouped by cluster membership and GO:BP annotation. Heatmap showing the average expression levels of SE dysregulated genes associated with the following GO Biological Process terms: Antigen processing and presentation of exogenous peptide antigen, Long term memory, Regulation of chaperone-mediated autophagy, Microglial cell activation and Synapse pruning. Expression values are grouped by condition, cluster membership and time point. The SE dysregulated genes correspond to genes identified as differentially expressed between SE and CTRL conditions.

Fields of Study & Subjects

Epilepsy research and treatment Neuroinflammation and Neurodegeneration Mechanisms Neuroscience and Neuropharmacology Research

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Language
EN