Association between triglyceride-glucose index and AVSS-rigiscan test parameters in men with erectile dysfunction

Although elevated triglyceride-glucose (TyG) index has been shown to affect penile erection, the relationship between the TyG index and erection at the tip or base of the penis has not been extensively studied. We investigated the effect of the TyG index on penile tip and base erection through a retrospective analysis, including 276 patients with erectile dysfunction (ED) as the case group and 28 men without sexual dysfunction (from health checkups or premarital examinations) as the control group. The correlation between TyG index levels and penile tip/base erection was analyzed. We found that TyG index levels were negatively correlated with the average event rigidity of the tip (r = −0.220; p = 0.0001), the average event rigidity of the base (r = −0.143; p = 0.013), and the average maximum rigidity of the tip (r = −0.165; p = 0.004). Additionally, TyG index levels showed a negative correlation with ∆ tumescence of the tip (r = −0.124; p = 0.031). Our data indicate that elevated TyG index is significantly associated with ED, and TyG index levels are negatively correlated with the parameters of the AVSS-RigiScan test.