Additional file 2 of HDAC11 interacts with the NuRD (MTA3) complex to transcriptionally suppress TGFβ1 expression and inhibit hepatocellular carcinoma metastasis

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Authors: Yang Yang, Jiaoli Wang, Q. Jackie Wu, Yishan Wang, Hui Meng, Lulu Zeng, Tian Autumn Qiu, Haixia Zhao, Qin Hu, Qiaoyou Weng, Meiling Liu, Minjiang Chen
+3 more Rongfang Qiu, Jiansong Ji, Weiqian Chen
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Abstract

Supplementary Material 2: Supplementary figure 1. Hematoxylin and eosin (HE) staining of lung tissues from mice to detect metastatic foci in different groups. B. KEGG pathway analysis of the HDAC11 interacting proteins identified by mass spectrometry. C. Immunoprecipitation analysis of HDAC11 with MTA1 and MTA2. Immunoprecipitation assays were performed in MHCC97H and HCCLM3 cells using antibodies against MTA1 or MTA2. The immunoprecipitates were subsequently analyzed by western blotting with an anti-HDAC11 antibody to detect the interactions between HDAC11 and MTA1 or MTA2 proteins.

Fields of Study & Subjects

Histone Deacetylase Inhibitors Research Mechanisms of cancer metastasis Epigenetics and DNA Methylation

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Language
EN