Supplementary Material for: URINARY BIOMARKER PROFILES DEFINE DIVERGENT PATHWAYS IN ALBUMINURIC AND NON-ALBUMINURIC DIABETIC KIDNEY DISEASE

Figshare 2026 Open access

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Authors: figshare admin karger, Kaygusuz Y., Deniz Aral Özbek, Erdut A., Rukiye Abanoz, Melek Günindi Korkut, Murat Özdede, Uyaroğlu O.A., Özmen F., Hacı Hasan Yeter, Yıldırım T., Yılmaz Ş.R.
+3 more Arıcı M., Erdem Y., Altun B.
DOI: 10.6084/m9.figshare.31323478
Cited by: 0

Abstract

Background: Diabetic kidney disease (DKD) presents with distinct phenotypes, including albuminuric (ADKD) and non-albuminuric DKD (NADKD), which are not fully distinguished by conventional clinical markers. This study aimed to evaluate urinary biomarkers indicative of nephron injury—nephrin, epidermal growth factor (EGF), vascular cell adhesion molecule-1 (VCAM-1), interleukin-18 (IL-18), and Rac-1 (Ras-related C3 botulinum toxin substrate) across various DKD phenotypes. Methods: In this cross-sectional study, 211 patients with type 2 diabetes mellitus were categorized into four groups based on estimated glomerular filtration rate (eGFR ≥ or

Fields of Study & Subjects

Chronic Kidney Disease and Diabetes Renal Diseases and Glomerulopathies Acute Kidney Injury Research

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Language
EN