16S rRNA sequencing
Abstract
This dataset supports a study investigating the microbiota-dependent, multi-target effects of Caralluma tuberculata (CT), a traditional edible plant, on hyperuricemia (HU). Using an AI-guided pipeline integrating graph convolutional networks and large language models, over 710,000 natural compounds were screened to identify CT bioactives. The dataset includes multi-omics and functional validation in murine HU models, and intestine/liver transcriptomics.
Fields of Study & Subjects
Gout
Hyperuricemia
Uric Acid
Computational Drug Discovery Methods
Gut microbiota and health
Publication details
- Journal / source
- Figshare
- Publication date
- 1 January 2026
- Language
- EN
- Document type
- Dataset