Additional file 1 of Association of DNA methylation with hypertension and blood pressure: a 7-year longitudinal study from KORA F4/FF4

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Authors: Liye Lai, Angelina Shin Yee Jong, Thomas Delerue, Jiesheng Lin, Barbara Thorand, Margit Heier, Holger Prokisch, Aiman Farzeen, Juliane Winkelmann, Elisabeth Thiering, Christian Gieger, Annette Peters
+1 more Melanie Waldenberger
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Abstract

Additional file 1: Text S1. Selection criteria of individuals in KORA F4 and FF4. Text S2. CPACOR Preprocessing Pipeline. Text S3. Selection criteria of CpG sites in KORA F4 and FF4. Text S4. Quality control for KORA FF4 gene expression data. Text S5. DNA methylation and gene expression analysis. Table S1. Characteristics of the study population: overall cohort and participants with repeated measurements. Figure S1. Manhattan plots of sensitivity analysis. Table S2. Summary of significant CpG sites associated with hypertension persistence. Table S3. Significant associated CpGtranscript pairs.

Fields of Study & Subjects

Epigenetics and DNA Methylation Blood Pressure and Hypertension Studies Genetic Associations and Epidemiology

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Language
EN