Proteomic Dataset of Differentially Expressed Proteins in MDA-MB-231

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Authors: Syed Haseeb Zia, Zhihao Wang, Yue Liu, Jingyi Wei, Wenwen Zhang, Silin Du, Jiazheng Liu, Junming Hu, Ying Li, Siyu Wei, Jiaxin Zhang, Zhao Liu
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Abstract

This dataset contains quantitative proteomic data from MDA-MB-231 triple-negative breast cancer (TNBC) cells treated with artesunate compared to untreated control cells.Each entry includes: UniProt accession number, protein name, gene name, mean intensity values for the artesunate-treated group (Artesunate Mean) and control group (NC Mean),p-value, fold change (FC), and regulation status (UP / Down / Non-significant).Proteomic sequencing was performed at the School of Pharmacy, Xuzhou Medical University. This dataset supports the manuscript: 'Artesunate Induces Autophagy Dependent Apoptosis in Triple-Negative Breast Cancer through TGM2 Mediated ROS-AMPK-mTOR axis', submitted to Scientific Reports (Springer Nature), 2026.

Fields of Study & Subjects

Autophagy in Disease and Therapy Advanced Proteomics Techniques and Applications Cell death mechanisms and regulation

Publication details

Journal / source
Figshare
Publication date
1 January 2026
Language
EN
Document type
Dataset