RGS19 is associated with prognosis and immune infiltration in glioma: an integrated bioinformatics analysis
Abstract
The regulator of G-protein signaling (RGS) family is involved in the malignant progression of several cancers, but has not been adequately studied in glioma. Six RGS genes with differential expression were evaluated using differential expression analysis. Four genes, including RGS19, which correlated with the prognosis, were screened. A nomogram was completed by the ‘rms’ package. The correlation between RGS19 and immune infiltration was analyzed using the TIMER website, the ‘GSVA’ and ‘estimate’ packages. The GO and KEGG annotation analyses were completed by the ‘clusterProfiler’ package to screen potential signaling pathways associated with RGS19.
Fields of Study & Subjects
Glioma Diagnosis and Treatment
Ferroptosis and cancer prognosis
Cancer-related molecular mechanisms research
Publication details
- Journal / source
- Figshare
- Publication date
- 26 February 2026
- Language
- EN