Supplementary Material for: Prediabetes in Children and Adults with Glomerular Disease

Background: Glomerular disease (GD) and diabetic nephropathy are both leading causes of end-stage kidney disease (ESKD) in the United States. Much is known about each individually, but less of any interactions between the two. There is emerging evidence that factors specific to glomerular disease, such as immunosuppression, may increase the risk of diabetes, which in turn could compound glomerular filtration rate (GFR) decline through the mechanisms of diabetic nephropathy. Understanding the epidemiology of prediabetes and diabetes in glomerular disease patients may inform improved screening and prevention practices in this population and may lead to strategies that mitigate progression to ESKD. The aim of this study is to delineate risk factors for prediabetes in glomerular disease. Methods: Data was extracted from University of Michigan and Kidney Research Network electronic health record registry with patients classified by age at glomerular disease at diagnosis or first nephrology appointment (child (age