P. aeruginosa ExoY inhibits ExoS-induced caspase activation in PMVECs Supplemental Figure 5

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Authors: Connor Holm, Phoibe Renema
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Abstract

ExoS significantly reduces ExoY+-induced cGMP production. PMVECs were treated with HBSS or inoculated with P. aeruginosa at an MOI of 20:1 for 5.5 hours. Whole cell lysates were collected in 0.1M HCl. Total cGMP concentrations were assessed by ELISA and normalized to total protein concentrations. Data were analyzed by one-way ANOVA with Tukey’s post hoc test. ns=not significant.

Fields of Study & Subjects

Bacterial biofilms and quorum sensing Bacterial Infections and Vaccines Escherichia coli research studies

Publication details

Journal / source
Figshare
Publication date
4 March 2026
Language
EN