Additional file 2 of Yixinshu attenuates myocardial infarction via SHP1/JAK2/STAT3-mediated regulation of mitochondrial function and apoptosis

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Authors: X Wang, Xinrui Wang, Yang Liu, Yang Cui, Keyi Chen, Hongkun Wu, Mingshan Zhang, Ming Liao, Linyun Fu, Xiangchun Shen
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Abstract

Supplementary Material 2. Fig.S2. YXS protected myocardial mitochondrial integrity and function. Stock solutions of YXS (2 g in 4 mL DMSO) or CDDP (4 g in 4 mL DMSO) were prepared with ice-bath sonication for 5 min, filtered through a 0.22-μm filter, and applied to cells. A Density of mitochondrial cristae and maximum width of mitochondrial cristae (n = 3). B Viability of primary cardiomyocytes (n = 5). C, D Assessment of mitochondrial membrane potential by JC-10 staining (scale bar = 25 μm) (n = 3). E Base peak chromatograms (BPCs) under positive ion mode. F BPCs under negative ion mode. Data were shown as mean ± SD. *p < 0.05, **p < 0.01 vs. sham or control group; #p < 0.05, ##p < 0.01 vs. MI or OGD group

Fields of Study & Subjects

Cardiac Ischemia and Reperfusion Traditional Chinese Medicine Analysis Cardiac Fibrosis and Remodeling

Publication details

Journal / source
Figshare
Publication date
4 March 2026
Language
EN