Additional file 2 of Yixinshu attenuates myocardial infarction via SHP1/JAK2/STAT3-mediated regulation of mitochondrial function and apoptosis
Abstract
Supplementary Material 2. Fig.S2. YXS protected myocardial mitochondrial integrity and function. Stock solutions of YXS (2 g in 4 mL DMSO) or CDDP (4 g in 4 mL DMSO) were prepared with ice-bath sonication for 5 min, filtered through a 0.22-μm filter, and applied to cells. A Density of mitochondrial cristae and maximum width of mitochondrial cristae (n = 3). B Viability of primary cardiomyocytes (n = 5). C, D Assessment of mitochondrial membrane potential by JC-10 staining (scale bar = 25 μm) (n = 3). E Base peak chromatograms (BPCs) under positive ion mode. F BPCs under negative ion mode. Data were shown as mean ± SD. *p < 0.05, **p < 0.01 vs. sham or control group; #p < 0.05, ##p < 0.01 vs. MI or OGD group
Fields of Study & Subjects
Cardiac Ischemia and Reperfusion
Traditional Chinese Medicine Analysis
Cardiac Fibrosis and Remodeling
Publication details
- Journal / source
- Figshare
- Publication date
- 4 March 2026
- Language
- EN