Additional file 2 of Genetic variants of pre-miRNA-499a and oxidative-immune biomarkers predict disease severity in rheumatoid arthritis

Supplementary Material 2. Supplementary Figure 1: Comparison of biochemical, antioxidant, inflammatory, and demographic parameters between healthy controls and rheumatoid arthritis (RA) patients. Bars represent mean ± SEM for each group (n = 50 for controls, n = 50 for RA). Statistically significant differences between groups were assessed using an independent t-test, and corresponding p-values are displayed above each parameter. Parameters include total antioxidant capacity (TAC), vitamin C, glutathione peroxidase (GPx), catalase, nitric oxide (NO), malondialdehyde (MDA), superoxide dismutase (SOD), interferon-gamma (IFN-γ), interleukin-10 (IL-10), zinc, copper, C-reactive protein (CRP), age, and body mass index (BMI). A p-value < 0.05 was considered statistically significant.