Reconceptualizing Dental Implant Integration: From Osseointegration-Based Fixation to Neuro-Guided Biological Integration

The figure contrasts two paradigms of dental implant integration. Conventional implantology relies on osseointegration, where implants are placed through osteotomy and screw-driven insertion to achieve direct bone–implant contact, resulting in stable mechanical fixation but loss of the natural periodontal proprioceptive function due to ankylotic integration. In contrast, the neuro-integrative A-Press protocol emphasizes atraumatic, nerve-preserving extraction, immediate socket press-fit implant placement, elastomeric neurogenic coating, and biologic soft-tissue sealing to support guided neural interface formation. This approach aims to move beyond purely structural anchorage toward biologically mediated, neurofunctionally integrated implants with preserved proprioceptive pathways.