Supplementary Material for: Kidney, pituitary, eyes and nose involved in Antineutrophil cytoplasmic antibody-associated vasculitis: A case report and literature review

Introduction:Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease characterized by diverse clinical manifestations. Central diabetes insipidus resulting from pituitary involvement in AAV is exceedingly rare. Case Presentation:This article presents a rare case of a young patient with a medical history of 8 years, who presented with sinusitis, pituitary microadenoma with central diabetes insipidus, acute renal injury, right abducens nerve paralysis (strabismus, diplopia), and most cases were not accompanied by an increase of ANCA titer. Conclusion: Our case showed that the GPA has a variety of clinical manifestations and rapid progression. The importance of timely diagnosis and treatment for the patient's prognosis.