Intracellular complement factor H protects neurons during CNS inflammation

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Authors: Christina Mayer, Marcel S. Woo, Jana K. Sonner, Lars Binkle-Ladisch, Felix Fischbach, Patricia Sekol, Matthew D. Smith, Fernando Lucas‐Ruiz, Darwin Manteufel, Kuno M.-J. Mattern, Lena Kristina Pfeffer, Yubing Guo
+19 more Bente Siebels, Albert Miguela, Vanessa Vieira, Nina Meurs, Simone Bauer, Sophia Schwarz, Sonia Wulf, Anne Mühlig, Jan Broder Engler, Marcus Conrad, Florence M. Bareyre, Thorsten Wiech, Susanne Krasemann, Markus Glatzel, Peter F. Zipfel, Tilo Freiwald, Peter A. Calabresi, Lucas Schirmer, Manuel Alexander Friese
Cited by: 1

Abstract

This repository contains the processed single-nucleus RNA sequencing data underlying the manuscript "Intracellular complement factor H protects neurons during CNS inflammation". The dataset includes raw count matrices after quality control and corresponding cell-level metadata for human retinal ganglion cells from control donors and donors with multiple sclerosis.

Publication details

Journal / source
Figshare
Publication date
28 July 2026
Document type
Dataset