Efektivitas Pemberian Tolvaptan pada Pasien Gagal Jantung dengan Resistensi Diuretik

Vitamin Jurnal ilmu Kesehatan Umum 2026 Open access

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Authors: Suzette Deby Claudia Daniel, Devina Sagitania
DOI: 10.61132/vitamin.v4i1.2093
Cited by: 0

Abstract

Diuretic resistance is a serious complication in heart failure patients associated with increased morbidity and mortality. Tolvaptan, a vasopressin V2 receptor antagonist, offers an alternative therapeutic mechanism through aquaresis. This study aims to evaluate the effectiveness and safety of tolvaptan in heart failure patients with diuretic resistance. A retrospective cohort study was conducted on 58 hospitalized patients with NYHA III-IV heart failure and diuretic resistance (urine output

Fields of Study & Subjects

Heart Failure Treatment and Management Electrolyte and hormonal disorders Ion Transport and Channel Regulation

Publication details

Journal / source
Vitamin Jurnal ilmu Kesehatan Umum
Volume
4
Issue
1
Pages
185–195
Publication date
31 January 2026
Language
EN