Clinical work perception and mental health in Danish resident doctors

INTRODUCTION: The transition from medical school to clinical practice is a demanding phase for junior doctors. This study examined associations between clinical work perceptions, mental health and pre-graduate clinical experience among Danish junior doctors, focusing on early training experiences and well-being. METHODS: A cross-sectional survey was sent to junior doctors in the North Denmark Region. The questionnaire was developed with input from junior doctor focus groups and included validated items from the Copenhagen Psychosocial Questionnaire, the WHO-5 Well-Being Index and the Major Depression Inventory. RESULTS: Overall, 297 junior doctors (38% response rate) completed the survey. Whereas the majority (66-79%) reported positive perceptions of the introduction, supervision and preparedness, 25% doubted their ability to remain in the profession. Approximately one-third reported exhaustion or stress more than half the time. Moreover, 13% scored below 35 on the WHO-5 Well-Being Index, indicating a high risk of stress-related disorders. Overall, 18% had a Major Depression Inventory score ≥ 20, consistent with depression. Pre-graduate locum experience was significantly associated with greater perceived preparedness and confidence, but not reduced stress or depressive symptoms. CONCLUSIONS: Substantial mental health concerns exist among Danish junior doctors. Pre-graduate experience enhances confidence but not emotional resilience. Institutional measures, such as structured supervision, mentorship and targeted well-being support, are needed in early medical careers. FUNDING: None. TRIAL REGISTRATION: Registration F2025-058.