Deprescribing methadone for chronic non-cancer pain: management of withdrawal symptoms
Abstract
In this case report, a 60-year-old patient was referred to a multidisciplinary pain clinic to discontinue methadone. Before referral, a self-managed dose reduction from 40 to 15 mg had led to loss of function due to withdrawal symptoms. After referral, methadone was successfully deprescribed over three months. Withdrawal symptoms were managed through an individually tailored plan, supportive consultations with a nurse, and the use of clonidine. The patient regained function after deprescribing methadone. Deprescribing opioids can be managed through a patient-centered approach and close monitoring.
Fields of Study & Subjects
Opioid Use Disorder Treatment
Pain Management and Opioid Use
Pharmaceutical Practices and Patient Outcomes
Publication details
- Journal / source
- Ugeskrift for Læger
- Volume
- 188
- Issue
- 10
- Pages
- 1–4
- Publication date
- 2 March 2026
- Language
- DA