Correlation of serum exosomal miR-21 with the risk of gastric cancer onset: its value for early diagnosis
Abstract
OBJECTIVES: This research explored the connection between serum exosomal miR-21 expression and the risk of gastric cancer (GC), and evaluated the viability of using this non-invasive marker for early GC diagnosis. METHODS: A retrospective evaluation was performed on 539 individuals who had received serum exosomal miR-21 testing. Based on diagnoses within 12 months, patients were categorized into a GC group (n=235) and a non-GC group (n=304). To measure the levels of exosomal miR-21, we used the technique of reverse transcription quantitative polymerase chain reaction (RT-qPCR). RESULTS: (Hp) infection, and family history of GC (all P
Fields of Study & Subjects
Extracellular vesicles in disease
MicroRNA in disease regulation
Vasculitis and related conditions
Publication details
- Journal / source
- American Journal of Translational Research
- Publisher
- e-Century Publishing Corporation
- Volume
- 18
- Issue
- 2
- Pages
- 1088–1102
- Publication date
- 1 January 2026
- Language
- EN