Gene polymorphisms and occurrence of type 2 diabetes in a Gabonese population
Abstract
BACKGROUND: of SLC30A8 in a Gabonese population with T2DM. METHOD: This case-control study was conducted at the Endocrinology Department of the University Hospital of Libreville. We enrolled 97 patients with T2DM and, from the general population, 87 control subjects who met the inclusion criteria. Genomic DNA was extracted with the Qiagen kit, and polymorphisms were analyzed using the RFLP method. RESULTS: (TCF7L2) were significantly associated with T2DM (P=0.021 and P=0.026, respectively). CONCLUSION: variant of TCF7L2 were associated with the occurrence of T2DM in this population.
Fields of Study & Subjects
Genetic Associations and Epidemiology
Diabetes and associated disorders
Nutrition
Genetics
and Disease
Publication details
- Journal / source
- International Journal of Biochemistry and Molecular Biology
- Volume
- 17
- Issue
- 1
- Pages
- 1–9
- Publication date
- 1 January 2026
- Language
- EN