Echocardiographic parameters for left ventricular function assessment and predictive value in coronary heart disease patients undergoing elective percutaneous coronary intervention

OBJECTIVE: To evaluate the prognostic value of specific echocardiographic parameters, particularly myocardial strain indices, in patients with coronary heart disease (CHD) undergoing elective percutaneous coronary intervention (PCI). METHODS: This retrospective study included 135 CHD patients who underwent PCI (observation group) and 100 healthy controls. Echocardiographic parameters (cardiac output [CO], left ventricular volumes [LVESV, LVEDV], ejection fraction [LVEF], cardiac index [CI], global longitudinal strain peak [GLSP], and global radial strain peak [GRSP]) were measured. Patients were followed up for 12 months post-PCI. Prognosis was determined based on the occurrence of major adverse cardiovascular events (MACE) during this follow-up period, including recurrent angina, acute coronary syndrome, arrhythmia, or heart failure. A good prognosis was defined as event-free survival with improved quality of life, while a poor prognosis was defined by the occurrence of any MACE. Parameters were compared between groups and correlated with prognosis. RESULTS: Pre-PCI, CHD patients had impaired parameters (lower CO, LVEF, CI; higher LVESV, LVEDV) versus controls (all P