Analysis of influencing factors of recurrence after thoracoscopic resection in patients with Stage I a lung adenocarcinoma
Abstract
This study aimed to investigate the influencing factors of recurrence after thoracoscopic resection in patients with Stage I a lung adenocarcinoma. The derivation cohort consisted of 104 patients admitted between February 2020 and December 2021, categorized into recurrence (n = 39) and non-recurrence (n = 65) groups based on postoperative recurrence status. Internal validation was performed using 10-fold cross-validation. Additionally, a temporally distinct validation cohort of 80 patients admitted between January 2022 and April 2022 was used for external validation, with similar recurrence-based grouping (relapse: n = 30; non-recurrent: n = 50). Univariate analysis revealed significant differences in age, maximum tumor diameter, pleural invasion, tumor differentiation, number of lymph node dissections, comorbidities, family history, and smoking history (P
Fields of Study & Subjects
Lung Cancer Diagnosis and Treatment
Inflammatory Biomarkers in Disease Prognosis
Lung Cancer Research Studies
Publication details
- Journal / source
- American Journal of Cancer Research
- Publisher
- e-Century Publishing Corporation
- Volume
- 16
- Issue
- 3
- Pages
- 840–852
- Publication date
- 1 January 2026
- Language
- EN