Why have extracorporeal carbon dioxide removal clinical trials failed?

Critical Care Science 2026 Open access

Read full text
Authors: Yuri de Albuquerque Pessoa dos Santos, Eduardo Leite Vieira Costa, Pedro Vitale Mendes, Marcelo Park, Bruno Adler Maccagnan Pinheiro Besen
DOI: 10.62675/2965-2774.20260266
Cited by: 2
References: 16

Abstract

INTRODUCTION Extracorporeal carbon dioxide removal (ECCO2R) is designed to eliminate carbon dioxide (CO2) from the blood.() Despite its theoretical advantages, current evidence does not support its routine clinical use outside of clinical trials, due to possible complications and the lack of benefit in the latest clinical trial.() From this viewpoint, we discuss possible reasons why […]

Fields of Study & Subjects

Mechanical Circulatory Support Devices Cardiac and Coronary Surgery Techniques Abdominal Surgery and Complications

Publication details

Journal / source
Critical Care Science
Publisher
Associação de Medicina Intensiva Brasileira
Volume
38
Pages
e20260266–e20260266
Publication date
1 January 2026
Language
EN