Delayed Serum Sickness after Immunosuppressive Therapy with Horse Antithymocyte Globulin in Severe Aplastic Anaemia: A Case Report
Abstract
Serum sickness (SS) is an immune-complex–mediated illness that frequently occurs in patients after polyclonal antibody therapy, such as thymoglobulin. Although SS has been described secondary to thymoglobulin therapy in adults, the administration of horse antithymocyte globulin (ATG) has been associated with SS in 1% to 10% of cases. Early recognition and accurate diagnosis are key for managing thymoglobulin-induced SS, as treatment is highly effective in achieving good outcomes.
Fields of Study & Subjects
Drug-Induced Adverse Reactions
Renal Transplantation Outcomes and Treatments
Immunodeficiency and Autoimmune Disorders
Publication details
- Volume
- III
- Issue
- 01
- Publication date
- 12 March 2026
- Language
- EN