Integrative Review of an Ayurvedic Polyherbal Formulation for the Management of Hypertension: Ayurvedic and contemporary Perspectives

Introduction: Hypertension is a major global health disorder contributing significantly to cardiovascular morbidity and mortality. Although several antihypertensive drugs are available, long-term therapy is frequently associated with adverse effects, economic burden, and poor patient compliance. Ayurveda describes conditions comparable to hypertension through concepts such as Vyānabala Vaiṣamya, Sirāgata Vāta, and Raktagata Vāta, emphasizing systemic balance and cardiovascular stability. Methods: A narrative review of classical Ayurvedic literature and contemporary biomedical studies was conducted to evaluate a polyherbal formulation containing Tagara (Valeriana wallichii), Arjuna (Terminalia arjuna), Jatāmāṁsī (Nardostachys jatamansi), Śaṅkhapuṣpī (Convolvulus pluricaulis), Rasona (Allium sativum), Aśvagandhā (Withania somnifera), and Gokṣura (Tribulus terrestris). Results: Literature suggests these herbs possess antihypertensive, cardioprotective, antioxidant, anxiolytic, adaptogenic, and vasorelaxant activities through autonomic modulation, endothelial protection, and oxidative stress reduction. Ayurvedic interpretation indicates normalization of Vāta and Rakta Duṣṭi with enhancement of Hṛdaya Bala. Discussion: The review demonstrates convergence between Ayurvedic concepts and modern hypertension pathophysiology, supporting future experimental and clinical evaluation of the formulation. Keywords: Hypertension, Ayurveda, Polyherbal formulation, Cardiovascular disease, Integrative medicine