FIBROMYALGIA: HORMONAL AND SOCIAL ASPECTS

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Authors: Hosana Marques Ferreira, Nelson Migani, Ana Beatriz Monteiro Rocha, Jorge Antônio Fortunato Costa, Anna Carolina Kirst, José Wandson Sousa da Costa, Emanuela Almeida Sobral
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Abstract

Fibromyalgia is a chronic syndrome characterized by widespread musculoskeletal pain, persistent fatigue, and cognitive and emotional disturbances, predominantly affecting women of working age. This chapter aims to analyze the main hormonal and social aspects associated with fibromyalgia, highlighting their influence on symptom onset, severity, and management. The methodology consisted of a narrative literature review based on national and international studies published in recognized scientific databases, addressing hormonal alterations—such as dysfunctions of the hypothalamicpituitary-adrenal axis, estrogen, cortisol, and serotonin—and social determinants of health, including gender, stigma, socioeconomic conditions, and social support. The results indicate that hormonal imbalances contribute to pain amplification and to mood and sleep disturbances, while social factors directly affect access to diagnosis, treatment adherence, and quality of life. It is concluded that fibromyalgia should be understood from a biopsychosocial perspective, emphasizing the importance of integrating clinical, hormonal, and social approaches to ensure more effective and humanized care.

Fields of Study & Subjects

Fibromyalgia and Chronic Fatigue Syndrome Research Psychosomatic Disorders and Their Treatments Myofascial pain diagnosis and treatment

Publication details

Journal / source
Aurum Editora eBooks
Pages
80–87
Publication date
14 January 2026
Document type
Book chapter