Langerhans cell histiocytosis (eosinophilic granuloma) with the orbital roof lesion: clinical observation
Abstract
Eosinophilic granuloma represents a subtype of histiocytosis, a benign tumor-like condition characterized by aberrant proliferation of antigenpresenting Langerhans cells derived from dendritic cells. This article presents a clinical case of a patient admitted with complaints of left upper eyelid edema and pain in the periorbital and temporal regions. Imaging studies revealed an intraosseous soft tissue lesion on the left side of the orbital roof. Surgical excision of the tumor was performed, and histological analysis of the biopsy specimen confirmed the diagnosis of eosinophilic granuloma.
Fields of Study & Subjects
Histiocytic Disorders and Treatments
Bone Tumor Diagnosis and Treatments
Ocular Oncology and Treatments
Publication details
- Journal / source
- Russian journal of neurosurgery
- Volume
- 27
- Issue
- 4
- Pages
- 74–79
- Publication date
- 15 January 2026