NEUROSPECIFIC ENOLASE INDICATORS IN EARLY DETECTION OF PERINATAL MNT INJURY IN INFANTS BORN SMALL FOR GESTATIONAL TERM

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Authors: Ishniyazova Nadira
Cited by: 0

Abstract

This study aimed to investigate the diagnostic value of neuro-specific enolase (NSE) levels for the early detection of perinatal central nervous system (CNS) injury in infants with small gestational age. The study analysed NSE levels, clinical signs, and neurosonographic changes in infants with small gestational age (SGA) and a healthy control group. The results demonstrated that NSE levels were significantly elevated in GTMKT infants, allowing early detection of CNS injury. The increase in NSE levels correlated with clinical signs such as decreased muscle tone, weakened reflexes, and autonomic disturbances. Furthermore, dynamic monitoring helps assess the cellular recovery process or the severity of injury. The study results confirm that evaluating NSE levels is an important tool for improving neonatal screening and therapeutic approaches. This approach contributes to supporting healthy infant development and reducing the risk of complications.

Fields of Study & Subjects

Neonatal and fetal brain pathology Neonatal Health and Biochemistry Neonatal and Maternal Infections

Publication details

Journal / source
Scientific and Innovative Therapy
Volume
5
Issue
1
Pages
1342–1358
Publication date
1 January 2026
Language
EN