Longitudinal dynamics of respiratory microbiome composition in infants after tracheostomy placement

medRxiv 2026 Preprint Open access

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Authors: Rebecca L. Steuart, Samantha Nicole Atkinson, Lucas R. Hoffman, Long T. Hung, Xiangming Ding, Nita Salzman, Christopher J. Russell
DOI: 10.64898/2025.12.29.25342834
Cited by: 0
References: 10

Abstract

Abstract Abnormal respiratory microbiomes are reported in children with artificial airways, yet the timing and persistence of these disruptions have not been defined in infants following new tracheostomy placement. We conducted a prospective longitudinal study to characterize airway microbiome dynamics following new tracheostomy placement during early life, a critical period for microbiome development. Fifteen hospitalized infants

Fields of Study & Subjects

Tracheal and airway disorders Gut microbiota and health Nosocomial Infections in ICU

Publication details

Journal / source
medRxiv
Publication date
2 January 2026
Language
EN
Document type
Preprint