Predictive value of Acute Physiology and Chronic Health Evaluation II (APACHE II) scoring in patients admitted to intensive care units

Abstract Background Risk stratification tools are essential for guiding care and allocating limited resources in intensive care units (ICUs). Evidence on the performance of the Acute Physiology and Chronic Health Evaluation II (APACHE II) score in Nepal is limited. We evaluated the association of APACHE II measured within 24 hours of ICU admission with mortality, ICU length of stay, and discharge disposition in a tertiary hospital in Nepal. Methods and findings We conducted a prospective observational cohort study of consecutive adult patients admitted to three multidisciplinary ICUs at a tertiary hospital in Kathmandu, Nepal. Patients with ICU stay