Links of Common Infections with Sleep in Middle-Aged and Older Adults: Modification by Race in the Baltimore Epidemiologic Catchment Area Study

Abstract Objectives To determine associations of common infections with self-reported sleep and explore whether these links differ by race in a diverse cohort. Methods We studied 602 participants from the Baltimore Epidemiologic Catchment Area Study (mean age 59.0±12.8 years; 36.9% male; 35.6% minoritized adults) with data on common infections (IgG antibodies to herpes simplex virus type 1, cytomegalovirus, varicella zoster virus, Epstein-Barr virus, and Toxoplasma gondii ) and self-reported symptoms of insomnia (i.e., difficulty falling or staying asleep and early awakening), hypersomnia, and sleep duration. Results We observed differences by race in the association of common infections with sleep disturbances (p-values for interactions