A Cross-Sectional Survey to Estimate the Prevalence of Family History of Colorectal, Breast, and Ovarian Cancer in Derna City, Libya

Abstract Background Family history of cancer is a well-established risk factor for several malignancies, including colorectal, breast, and ovarian cancers. Estimating the prevalence of familial cancer history is essential for identifying high-risk populations and guiding targeted prevention strategies. Objective This study aimed to estimate the prevalence of family history of colorectal, breast, and ovarian cancer among residents of Derna City, Libya. Methods A cross-sectional survey was conducted among 300 participants aged 17–45 years, selected using stratified random sampling. Data were collected through structured questionnaires covering sociodemographic characteristics and family history of cancer. Descriptive statistical analyses were performed to estimate prevalence rates. Results The mean age of participants was 24.65 ± 4.70 years, with the majority under 25 years of age (67.3%). Females constituted 79.9% of the sample, and most participants had a university-level education (93.5%). A family history of breast cancer was reported by 30.0% of participants, followed by colorectal cancer (23.3%) and ovarian cancer (13.3%). These findings indicate a substantial proportion of individuals with potential genetic susceptibility to these cancers within the study population. Conclusion A notable prevalence of family history of colorectal, breast, and ovarian cancers was observed in Derna City. These results underscore the importance of incorporating family history assessment into routine healthcare practice and strengthening genetic counseling, screening, and public awareness programs. Targeted prevention strategies may help reduce the burden of hereditary cancers in this region.