A whole organism screening platform identifies gut microbiome microproteins that modulate host metabolism

bioRxiv (Cold Spring Harbor Laboratory) 2026 Preprint Open access

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Authors: Nina E. Short, Eleanor C. Warren, Imani E. Porter, Yishay Pinto, Javier Rodriguez, Karen S. Sarkisyan, Ami Siddharth Bhatt, André EX Brown, David T. Riglar
DOI: 10.64898/2026.02.11.705328
Cited by: 0
References: 61

Abstract

Abstract Advances in metagenomic sequencing over the past two decades have identified vast numbers of previously uncharacterised small open reading frames that may encode microproteins (

Fields of Study & Subjects

Gut microbiota and health Genomics and Phylogenetic Studies Microbial Natural Products and Biosynthesis

Publication details

Journal / source
bioRxiv (Cold Spring Harbor Laboratory)
Publication date
12 February 2026
Language
EN
Document type
Preprint