Walking in the Free World: Establishing Normative Trajectories for Ecological Assessment of Robust Gait Variability with Age

View at publisher
Authors: Kai Zhe Tan, Kresimir Friganovic, Yong Kim, Angela Frautschi, Michelle Gwerder, Kok Yang Tan, Vanessa Jean Wen Koh, Rahul Malhotra, Angelique Wei-Ming Chan, David Bruce Matchar, Navrag B. Singh
Cited by: 1
References: 42

Abstract

Abstract Gait variability is a critical functional indicator of dynamic balance and neurocognitive decline in health. Its translation into clinical practice is, however, challenged by a lack of age-related normative trajectories and reference values under real-world ecological settings. Furthermore, the conventional metrics used to estimate gait variability (Coefficient of Variation, CV ; Standard Deviation, SD ) have a fundamental methodological flaw: the inherent sensitivity of conventional metrics to the statistical outliers and environmental noise in real-world walking. In this study, we mitigate this factor by applying a robust statistical framework to quantify gait variability. Analysing a large-scale cohort of community-dwelling older adults (n=2,193), we first demonstrate that freeliving gait data follows a heavy-tailed distribution, necessitating the use of robust estimators like the Robust Coefficient of Variation ( RCV MAD ) and Median Absolute Deviation ( MAD ). Leveraging these metrics, we established the normative trajectory and reference values of real-world gait variability across the ageing lifespan, revealing a distinct, age-dependent increase in spatio-temporal fluctuations, indicating a decline in rhythmicity and steadiness with age. We further demonstrated the clinical utility of these robust metrics: RCV MAD consistently yielded larger effect sizes than conventional CV in discriminating between fallers and non-fallers across all gait parameters. Furthermore, we illustrate the potential of long-term unsupervised monitoring to capture intrinsic variability during real-world walking. Validated for consistency and reliability, this robust framework provides the necessary ecological validity to transform gait variability into a standardised, rapid clinical metric for assessing functional decline at an early timepoint.

Fields of Study & Subjects

Balance Gait and Falls Prevention Gait Recognition and Analysis Cerebral Palsy and Movement Disorders

Publication details

Journal / source
medRxiv
Publisher
openRxiv
Publication date
6 March 2026
Document type
Preprint