The Cartilage Thickness Score (CTh-Score) detects a structural effect of 2-year weight loss: data from the Osteoarthritis Initiative

medRxiv 2026 Preprint Open access

Read full text
Authors: Paul Margain, Julien Favre, Françis Berenbaum, Patrick Omoumi
DOI: 10.64898/2026.04.01.26349854
Cited by: 1
References: 30

Abstract

Objective To determine whether clinically significant weight loss (≥5% of body weight) is associated with slower 2-year knee cartilage structural deterioration, using the Cartilage Thickness Score (CTh-Score). Method A retrospective propensity-score-matched cohort study was conducted using Osteoarthritis Initiative study data. Weight loss was defined as ≥5%; stable weight as

Fields of Study & Subjects

Osteoarthritis Treatment and Mechanisms Total Knee Arthroplasty Outcomes Lower Extremity Biomechanics and Pathologies

Publication details

Journal / source
medRxiv
Publisher
openRxiv
Publication date
2 April 2026
Document type
Preprint