SCALP MICROBIOME IN ALOPECIA: A NEW DIRECTION IN TRICHOLOGICAL DIAGNOSTICS AND FOLLICLE RESTORATION

The theoretical issues of the formation of the epidermal barrier of the skin (with the participation of keratinocytes and individual non-keratinocytes of the epidermis), the participation of skin appendages (sebaceous glands and sweat glands) in its formation are investigated. The main points of the coexistence of skin components and the most numerous representatives of the skin microbiome, which form the basis of the dynamic equilibrium inherent in the concept of "healthy skin", are considered. The main pathogenetic mechanisms in the development of skin diseases, including scalp diseases and the causes of hair loss, associated or not associated with changes in the skin microbiota, are highlighted. Certain existing and certain possible ways and methods of correcting pathological skin conditions, including scalp diseases, accompanied by alopecia, are highlighted. 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