Multiple endocrine neoplasia syndrome type 1: clinical case

Multiple endocrine neoplasia syndrome type 1 (MEN 1, Wermer syndrome) is a group of heterogeneous inherited diseases, caused by hyperplasia or neoplastic transformation of several endocrine glands. MEN 1 syndrome is characterized by variable combinations of endocrine disorders. Cancer awareness in patient with diagnosed and genetically confirmed multiple endocrine neoplasia type 1 syndrome relatives plays an important role.This case demonstrates a non-classical manifestation of the disease with neuroendocrine tumor of the pancreas, accompanied by hiperinsulinemic hypoglycemia, and the subsequent detection of primary hyperparathyroidism.