Biochemical mechanisms of adaptation and metabolic disorders in women of reproductive age under the conditions of the environmental crisis of the Aral Sea region

The Aral Sea region is among the territories with the most pronounced and prolonged environmental distress, formed under the influence of natural-climatic and anthropogenic factors. Long-term exposure to adverse environmental conditions is accompanied by the development of chronic environmental stress and the formation of metabolic disorders in the population. This problem is of particular medical and social significance for women of reproductive age, whose health status determines the reproductive potential and demographic sustainability of the region. The article presents the results of an extended analysis of the biochemical status of women of reproductive age living under the conditions of the environmental crisis in the Aral Sea region. It is shown that chronic exposure to environmental risk factors leads to disturbances in protein and lipid metabolism, overstrain of detoxification systems, and the formation of prenosological conditions. The feasibility of using a complex of biochemical indicators in the system of preventive health monitoring of populations in environmentally disadvantaged areas is substantiated.