Antimicrobial Activity of Green Synthesized Silver Nanoparticles (Ag-NPs) using Curcuma caesia Rhizome Extract

Antibiotics revolutionized medicine, but misuse has fueled antimicrobial resistance, creating a global health crisis. As conventional antibiotics lose efficacy, nanotechnology offers promising alternatives, particularly silver nanoparticles (AgNPs) due to their broad-spectrum antimicrobial activity, low toxicity, and high biocompatibility. Green synthesis of nanoparticles using plant extracts is gaining attention as a sustainable, eco-friendly method, eliminating the need for toxic chemicals or high-energy processes. Curcuma caesia (black turmeric), a medicinal herb rich in phytochemicals like flavonoids, terpenoids, tannins, and curcuminoids, possesses well-documented antimicrobial, anti-inflammatory, and antioxidant properties, making it a potential candidate for nanoparticle synthesis. This study focuses on the green synthesis of AgNPs using C. caesia rhizome extract and evaluates their antimicrobial efficacy. The synergistic potential of plant-derived compounds and AgNPs may offer a novel therapeutic approach against resistant pathogens, bridging traditional medicine with modern nano-biotechnology.