Ultrasonic characteristics of cutaneous Rosai-Dorfman disease: A case study

Background: Cutaneous Rosai-Dorfman disease (CRDD) is an uncommon histiocytic proliferative disorder localized to the skin, representing merely 3% of all reported cases of Rosai-Dorfman disease (RDD).Despite numerous investigations into the clinical and pathological attributes of CRDD, there are few works on its ultrasonic manifestations, with the majority of studies being limited to individual case reports.Case presentation: This paper presents the case of a 66-year-old female who exhibited red nodules on the skin of her face, accompanied by pruritus, which persisted for 2 years and notably affected her quality of sleep.Clinical assessment substantiated a diagnosis of CRDD, and subsequent ultrasound imaging revealed a low-echo nodule.The nodule (2.4 cm by 0.4 cm) was identified within the skin of the right eyebrow and exhibited pronounced blood flow.Following multiple sessions of targeted treatment, there was a notable improvement in the lesion, and no recurrence was detected during subsequent follow-up evaluations.Conclusion: This case exemplifies the typical ultrasound features associated with CRDD and underscores the limitations inherent in ultrasound diagnostics, thereby highlighting the vital importance of histopathological assessment.