Perfil epidemiológico da hemofilia no estado da Bahia, 2020–2024.

Hemophilia is a rare hereditary coagulopathy linked to the X chromosome, caused by the deficiency of coagulation factors VIII (Hemophilia A) or IX (Hemophilia B), and characterized by recurrent bleeding episodes and progressive joint impairment. This study aimed to analyze the epidemiological profile of hemophilia in the state of Bahia, Brazil, between 2020 and 2024. This is an ecological, descriptive, and retrospective analysis based on secondary data obtained from official monitoring reports of hereditary coagulopathies published by the Specialized Health Care Secretariat (SAES), through the Department of Specialized and Thematic Care (DAET) and the General Coordination of Blood and Blood Products (CGSH) of the Brazilian Ministry of Health. The analyzed variables included prevalence, severity classification, consumption of factor VIII and IX concentrates, and therapeutic modalities. The results showed a predominance of Hemophilia A throughout the analyzed period, a higher frequency of moderate and severe cases, and a care model predominantly based on long-term secondary prophylaxis. Factor VIII consumption decreased in 2020 and increased in subsequent years, whereas factor IX consumption showed interannual variations. Overall, the time series suggests a trend toward epidemiological stability of hemophilia in Bahia. However, the absence of records related to the female population in the consulted databases may suggest informational gaps or limitations in data capture, highlighting the importance of improving surveillance and monitoring systems for hereditary coagulopathies in the state.