Glycemic Status in Pulmonary Tuberculosis Patient

Abstract Background: Tuberculosis (TB) is the leading infectious disease causing of death among adults worldwide. Chronic infections like TB, can induce transient hyperglycemia, TB cases are also more likely to have diabetes mellitus (DM) than the general population. Tuberculosis and altered glycemic status complicate each other at numerous levels. Prolonged hyperglycemic state doubles or triples the incidence of active tuberculosis and increases the risk of tuberculosis treatment failure and death, there may be altered glycemic status in patients with PTB. Currently world health organization (WHO) also recommends for such bi-directional screening as detecting early the co-existence of these diseases can lead to better management of both cases. So this study is aimed to assess the association of tuberculosis with the presence and persistence of hyperglycemia. Objective: To assess the glycemic status in pulmonary tuberculosis patients. Methods: This was a cross-sectional study conducted in department of Medicine and Department of Endocrinology, Rangpur Medical College Hospital and Tajhat Chest disease Hospital, Rangpur for 2 years (2021 - 2022). After careful history taking, examination and appropriate investigations fulfilling inclusion and exclusion criteria, total 100 patients with pulmonary tuberculosis, irrespective of their sex, race and ethnic group were included in this study. A semi-structured questionnaire was developed by using the selected variables according to the specific objectives. Data analysis was carried out by using SPSS (version 24). Results: On assessing glycemic status, 45% patients were diabetic. BMI of PTB patients of the study was statistically associated with diabetic status (p=0.021). Smoking had significant relation with diabetic status (p=0.012). Most of the patients were primary smoker. Most of the diabetic patients had history of diabetes in their family. Family history of diabetes was significantly associated with diabetic status (p