Front-Loading Fatigue: Does the Pre-exhaustion Method influence Resistance Training-induced Muscular Adaptations?

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Authors: Tom Hermann, Adam Eithen Mohan, Alec Piñero, Alysson Afonso Nadalin Enes, Max Coleman, Arman Zamanzadeh, Max Sapuppo, Albert Jia, Jeremy Ethier, Patroklos Koriakis, Milo Wolf, Paul Alan Swinton
+1 more Brad Jon Schoenfeld
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Abstract

This study aimed to compare the effects of pre-exhaust training and traditional training on muscular hypertrophy, strength, body composition, and muscular endurance in resistance-trained participants over an 8-week study period. We randomly assigned 48 young, resistance trained individuals (male = 32, female = 9; height = 173.0 ± 10.3 cm; weight = 81.7 ± 15.9 kg; age = 22.5 ± 4.1 yrs) to 1 of 2 experimental groups after initial testing: a pre-exhaust resistance training (RT) group (PreEx: n = 24) or a traditional RT group (TRAD: n = 24). The RT protocol consisted of the following lower body exercises: leg extension, Smith squat, seated hamstring curl, barbell Romanian deadlift. Participants in the TRAD group completed all sets for one exercise before performing a different exercise with ~2 minutes of rest between sets. The PreEx group performed a set of a single-joint exercise immediately prior (

Fields of Study & Subjects

Sports Performance and Training Cardiovascular and exercise physiology Muscle activation and electromyography studies

Publication details

Journal / source
International journal of exercise science
Publisher
Kinesiology Scholarly Trends, Abstracts, and Research
Volume
19
Issue
1
Pages
1008–1008
Publication date
1 January 2026
Language
EN