DETERMINATION OF TECHNOLOGICAL PROPERTIES OF DRY EXTRACT OF RUBIA TINCTORUM L.
Abstract
This study investigated the technological properties of a compressible mass intended for tablets used in the treatment of urolithiasis. Dry extracts of Rubia tinctorum (Bo‘yoqdor ro‘yan) was selected as active substance. Initial tests revealed unsatisfactory technological indicators: uneven particle size distribution, poor flowability, high compressibility coefficient, and excessive residual moisture. Application of the wet granulation method with lactose and starch as excipients significantly improved the mass properties, enhancing flowability, compressibility, and moisture balance. The obtained results provide a strong basis for producing stable and high-quality tablets in further stages of development.
Fields of Study & Subjects
Granular flow and fluidized beds
Drug Solubulity and Delivery Systems
Pharmacology and Nanomedicine Research
Publication details
- Journal / source
- Eurasian Journal of Medical and Natural Sciences
- Volume
- 6
- Issue
- 1
- Pages
- 77–85
- Publication date
- 12 January 2026
- Language
- EN