A Concise Review on Fast Dissolving Tablets

Fast dissolving tablets (FDTs) have emerged as one of the most innovative and patient-friendly oral dosage forms, offering a convenient solution for individuals who experience difficulty swallowing conventional tablets or capsules.They are especially advantageous for pediatric and geriatric patients, as well as for bedridden, psychiatric, or uncooperative individuals.FDTs disintegrate or dissolve rapidly in saliva, typically within 60 seconds, eliminating the need for water and allowing quick drug absorption through the buccal cavity.The formulation employs superdisintegrants to facilitate rapid disintegration and enhance drug bioavailability.Combining the advantages of both solid and liquid dosage forms, FDTs offer improved patient compliance, accurate dosing, and better chemical stability.Multiple technologies-including direct compression, spray drying, sublimation, melt granulation, lyophilization, phase transition, and mass extrusion-have been developed for their manufacture.This review summarizes the definition, need, formulation aspects, advantages, limitations, challenges, and marketed products of FDTs, highlighting their growing importance in modern pharmaceutical technology.